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KMID : 0043320060290100815
Archives of Pharmacal Research
2006 Volume.29 No. 10 p.815 ~ p.820
A New Monoterpene Glycoside and Antibacterial Monoterpene Glycosides from Paeonia suffruticosa
An Ren-Bo

Kim Hyun-Chul
Lee Sung-Hee
Jeong Gil-Saeng
Sohn Dong-Hwan
Park Hyun
Kwon Dong-Yeul
Lee John-Hwa
Kim Youn-Chul
Abstract
Antibacterial activity-guided fractionation of the CHCl3-MeOH (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to 500 ¥ìg/mL against eighteen pathogenic microorganisms of concern for public health or zoonosis.
KEYWORD
Paeonia suffruticosa, 6-O-Vanillyoxypaeoniflorin, Monoterpene glycoside, mudanpioside-H, Galloyl-oxypaeoniflorin, Antibacterial
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