KMID : 0043320060290100815
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Archives of Pharmacal Research 2006 Volume.29 No. 10 p.815 ~ p.820
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A New Monoterpene Glycoside and Antibacterial Monoterpene Glycosides from Paeonia suffruticosa
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An Ren-Bo
Kim Hyun-Chul Lee Sung-Hee Jeong Gil-Saeng Sohn Dong-Hwan Park Hyun Kwon Dong-Yeul Lee John-Hwa Kim Youn-Chul
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Abstract
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Antibacterial activity-guided fractionation of the CHCl3-MeOH (1:1) extract of Paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), mudanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to 500 ¥ìg/mL against eighteen pathogenic microorganisms of concern for public health or zoonosis.
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KEYWORD
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Paeonia suffruticosa, 6-O-Vanillyoxypaeoniflorin, Monoterpene glycoside, mudanpioside-H, Galloyl-oxypaeoniflorin, Antibacterial
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